PRP Education

How PRP Actually Works: Platelets, Growth Factors and Realistic Outcomes

Concentrated platelets release growth factors that recruit repair — here is what that means for skin and hair, without the marketing.

2 July 2026 · 6 min read

The biology

Spinning autologous blood concentrates platelets several-fold above baseline. On degranulation they release PDGF, TGF-beta, VEGF and EGF, which recruit fibroblasts and stimulate collagen and angiogenesis.

Where the evidence is strongest

Androgenetic alopecia and skin quality show the most consistent published benefit; volume replacement is not what PRP does.

Counselling patients honestly

Expect three sessions four weeks apart, gradual change over three months, and maintenance. Patients who are promised a facelift will be disappointed.

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